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Accueil du site > Séminaires LNC > séminaires à venir (upcoming seminars)

Séminaire LNC : Pierre Denise

Pierre Denise UMR INSERM Université de Caen Mobilités : Orientation, Attention et Chronobiologie

Titre : Perception de l’espace et régulations végétatives

Recently it has been shown that the vestibular system controls many autonomous regulations. In general, the effects of the vestibular system on the autonomous regulation are viewed as “reflexes”. But growing evidence from the animal studies supports the hypothesis that multiple sensory inputs are integrated to produce stable blood pressure during changes in posture. To determine the spatial position of the body, the central nervous system elaborates an internal representation of gravity. This representation is multimodal using several sensory inputs (visual, vestibular, somesthetic…). It is conceivable that, in the same way, the sympathetic activation during orthostatic regulation calls on an internal representation of the intravascular pressures, built on the same information as the internal representation of gravity. With this model any abrupt defect or modification of a sensory input would affect blood pressure control as long as a new reinterpretation is not developed.

We will present results of 2 experiments substantiating the hypothesis that the effect of the vestibular system on the cardiovascular system is not direct but is mediated by an internal representation of gravity.