Changes in the spatiotemporal pattern of spontaneous activity across a cortical column after noise trauma


  • Parameshwarappa V.
  • Pezard L.
  • Noreña A.

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The present study investigates the effects of acute and chronic noise trauma on the laminar pattern of spontaneous activity in the primary auditory cortex. Our study is first to report that noise trauma alters the sequence of cortical column activation during ongoing activity. In particular, we show that the supragranular layer becomes a major input recipient and the synaptic activity in the infragranular layers is enhanced.

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